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informazioni",{"id":2186,"_modelApiKey":2187,"__typename":2188,"title":2189,"html":2190},"PmOYIa0rS42AqggosIvxzA","resource","ResourceRecord","Riferimenti:","\u003Col style=\"margin-top: 0cm;\" start=\"1\" type=\"1\">\n\u003Cli class=\"MsoNormal\" style=\"mso-list: l1 level1 lfo1; tab-stops: list 36.0pt;\">World Health Organization Regional Office for Europe, ‘Cardiovascular diseases’, 17 July 2024, \u003Cb>Key facts\u003C\u002Fb>. Available at: \u003Ca href=\"https:\u002F\u002Fwww.who.int\u002Feurope\u002Fnews-room\u002Ffact-sheets\u002Fitem\u002Fcardiovascular-diseases\" target=\"_blank\" rel=\"noopener\">https:\u002F\u002Fwww.who.int\u002Feurope\u002Fnews-room\u002Ffact-sheets\u002Fitem\u002Fcardiovascular-diseases\u003C\u002Fa> (Accessed: 2 September 2026). \u003Co:p>\u003C\u002Fo:p>\u003C\u002Fli>\n\u003C\u002Fol>\n\u003Col style=\"margin-top: 0cm;\" start=\"2\" type=\"1\">\n\u003Cli class=\"MsoNormal\" style=\"mso-list: l4 level1 lfo2; tab-stops: list 36.0pt;\">Boutouyrie, P. and Bruno, R.-M., ‘The Clinical Significance and Application of Vascular Stiffness Measurements’, \u003Ci>American Journal of Hypertension\u003C\u002Fi>, 32.1 (2019), pp. 4–11. Available at: \u003Ca href=\"https:\u002F\u002Fdoi.org\u002F10.1093\u002Fajh\u002Fhpy145\" target=\"_blank\" rel=\"noopener\">https:\u002F\u002Fdoi.org\u002F10.1093\u002Fajh\u002Fhpy145\u003C\u002Fa> (Accessed: 2 September 2026). \u003Co:p>\u003C\u002Fo:p>\u003C\u002Fli>\n\u003C\u002Fol>\n\u003Col style=\"margin-top: 0cm;\" start=\"3\" type=\"1\">\n\u003Cli class=\"MsoNormal\" style=\"mso-list: l0 level1 lfo3; tab-stops: list 36.0pt;\">Van Bortel, L. M., Laurent, S., Boutouyrie, P., Chowienczyk, P., Cruickshank, J. K., De Backer, T. \u003Ci>et al.\u003C\u002Fi>, ‘Expert Consensus Document on the Measurement of Aortic Stiffness in Daily Practice Using Carotid-Femoral Pulse Wave Velocity’, \u003Ci>Journal of Hypertension\u003C\u002Fi>, 30.3 (2012), pp. 445–448. Available at: \u003Ca href=\"https:\u002F\u002Fdoi.org\u002F10.1097\u002FHJH.0b013e32834fa8b0\" target=\"_blank\" rel=\"noopener\">https:\u002F\u002Fdoi.org\u002F10.1097\u002FHJH.0b013e32834fa8b0\u003C\u002Fa> (Accessed: 2 September 2026). \u003Co:p>\u003C\u002Fo:p>\u003C\u002Fli>\n\u003C\u002Fol>\n\u003Col style=\"margin-top: 0cm;\" start=\"4\" type=\"1\">\n\u003Cli class=\"MsoNormal\" style=\"mso-list: l5 level1 lfo4; tab-stops: list 36.0pt;\">Ben-Shlomo, Y., Spears, M., Boustred, C., May, M., Anderson, S. G., Benjamin, E. J., Boutouyrie, P. \u003Ci>et al.\u003C\u002Fi>, ‘Aortic Pulse Wave Velocity Improves Cardiovascular Event Prediction: An Individual Participant Meta-Analysis of Prospective Observational Data from 17,635 Subjects’, \u003Ci>Journal of the American College of Cardiology\u003C\u002Fi>, 63.7 (2014), pp. 636–646. Available at: \u003Ca href=\"https:\u002F\u002Fdoi.org\u002F10.1016\u002Fj.jacc.2013.09.063\" target=\"_blank\" rel=\"noopener\">https:\u002F\u002Fdoi.org\u002F10.1016\u002Fj.jacc.2013.09.063\u003C\u002Fa> (Accessed: 2 September 2026). \u003Co:p>\u003C\u002Fo:p>\u003C\u002Fli>\n\u003C\u002Fol>\n\u003Col style=\"margin-top: 0cm;\" start=\"5\" type=\"1\">\n\u003Cli class=\"MsoNormal\" style=\"mso-list: l6 level1 lfo5; tab-stops: list 36.0pt;\">McEvoy, J. W., McCarthy, C. P., Bruno, R. M., Brouwers, S., Canavan, M. D., Ceconi, C. \u003Ci>et al.\u003C\u002Fi>, ‘2024 ESC Guidelines for the Management of Elevated Blood Pressure and Hypertension’, \u003Ci>European Heart Journal\u003C\u002Fi>, 45.38 (2024), pp. 3912–4018, especially section 6.4.3 and Recommendation Table 4. Available at: \u003Ca href=\"https:\u002F\u002Fdoi.org\u002F10.1093\u002Feurheartj\u002Fehae178\" target=\"_blank\" rel=\"noopener\">https:\u002F\u002Fdoi.org\u002F10.1093\u002Feurheartj\u002Fehae178\u003C\u002Fa> (Accessed: 2 September 2026). \u003Co:p>\u003C\u002Fo:p>\u003C\u002Fli>\n\u003C\u002Fol>\n\u003Col style=\"margin-top: 0cm;\" start=\"6\" type=\"1\">\n\u003Cli class=\"MsoNormal\" style=\"mso-list: l3 level1 lfo6; tab-stops: list 36.0pt;\">Mancia, G., Kreutz, R., Brunström, M., Burnier, M., Grassi, G., Januszewicz, A. \u003Ci>et al.\u003C\u002Fi>, ‘2023 ESH Guidelines for the Management of Arterial Hypertension’, \u003Ci>Journal of Hypertension\u003C\u002Fi>, 41.12 (2023), pp. 1874–2071, especially section 5.5.2.2 and Table 11. Available at: \u003Ca href=\"https:\u002F\u002Fdoi.org\u002F10.1097\u002FHJH.0000000000003480\" target=\"_blank\" rel=\"noopener\">https:\u002F\u002Fdoi.org\u002F10.1097\u002FHJH.0000000000003480\u003C\u002Fa> (Accessed: 2 September 2026). \u003Co:p>\u003C\u002Fo:p>\u003C\u002Fli>\n\u003C\u002Fol>\n\u003Col style=\"margin-top: 0cm;\" start=\"7\" type=\"1\">\n\u003Cli class=\"MsoNormal\" style=\"mso-list: l2 level1 lfo7; tab-stops: list 36.0pt;\">Podolec, P., Kopeć, G., Podolec, J., Wilkołek, P., Krochin, M., Rubiś, P. \u003Ci>et al.\u003C\u002Fi>, ‘Aortic Pulse Wave Velocity and Carotid-Femoral Pulse Wave Velocity: Similarities and Discrepancies’, \u003Ci>Hypertension Research\u003C\u002Fi>, 30.12 (2007), pp. 1151–1158. Available at: \u003Ca href=\"https:\u002F\u002Fdoi.org\u002F10.1291\u002Fhypres.30.1151\" target=\"_blank\" rel=\"noopener\">https:\u002F\u002Fdoi.org\u002F10.1291\u002Fhypres.30.1151\u003C\u002Fa> (Accessed: 2 September 2026). \u003Co:p>\u003C\u002Fo:p>\u003C\u002Fli>\n\u003C\u002Fol>",[],{"schema":2193,"document":2194},"dast",{"type":2195,"children":2196},"root",[2197,2207,2212,2216,2220,2224,2228,2230,2236,2240,2244,2248,2256,2260,2266,2270,2274,2278,2282,2283,2289,2293,2297,2301,2307,2311,2317,2321,2327,2331,2335,2341,2345,2346,2349,2355,2390,2393,2396,2402,2406,2409,2410],{"type":2198,"level":435,"children":2199},"heading",[2200,2205],{"type":2201,"marks":2202,"value":2204},"span",[2203],"strong","La professoressa Rosa Maria Bruno sull’invecchiamento vascolare, la prevenzione e l’identificazione precoce delle persone che necessitano di maggiore attenzione",{"type":2201,"value":2206}," ",{"type":2208,"children":2209},"paragraph",[2210],{"type":2201,"value":2211},"Nella prevenzione cardiovascolare, l’età è uno dei fattori più influenti nella valutazione del rischio. È anche uno dei motivi per cui i cambiamenti precoci possono essere difficili da riconoscere. ",{"type":2208,"children":2213},[2214],{"type":2201,"value":2215},"Una persona più giovane può avere un basso rischio cardiovascolare calcolato a breve termine, mentre le sue arterie hanno già iniziato a risentire degli effetti cumulativi dell’ipertensione, di fattori metabolici, dello stile di vita o di altre esposizioni. Due persone della stessa età e con misurazioni di routine simili possono quindi non avere la stessa salute vascolare. ",{"type":2208,"children":2217},[2218],{"type":2201,"value":2219},"La questione è rilevante in tutta Europa. Le malattie cardiovascolari restano la prima causa di morte e disabilità nella Regione europea dell’OMS. Nel 2019 hanno causato circa 4,2 milioni di decessi, pari al 42,5% di tutti i decessi nella Regione.¹ ",{"type":2208,"children":2221},[2222],{"type":2201,"value":2223},"La prevenzione non riguarda quindi solo la risposta a una malattia già manifesta, ma anche l’identificazione delle persone il cui rischio merita attenzione prima della comparsa di sintomi o eventi acuti. ",{"type":2208,"children":2225},[2226],{"type":2201,"value":2227},"Questo è stato il tema centrale della presentazione della professoressa Rosa Maria Bruno alla MESI Conference 2026. Professoressa all’Université Paris Cité e responsabile dell’unità di farmacologia clinica dell’Hôpital Européen Georges Pompidou di Parigi, si occupa di invecchiamento vascolare e di come la valutazione non invasiva possa aiutare a identificare persone il cui rischio non emerge completamente dalle misurazioni convenzionali. ",{"item":2145,"type":2229},"block",{"type":2198,"level":435,"children":2231},[2232,2235],{"type":2201,"marks":2233,"value":2234},[2203],"L’età cronologica non racconta tutta la storia",{"type":2201,"value":2206},{"type":2208,"children":2237},[2238],{"type":2201,"value":2239},"Le arterie non invecchiano allo stesso ritmo in ogni persona. Ipertensione, diabete, malattia renale cronica, fumo e altri fattori di rischio cardiovascolare a lungo termine possono accelerare le modifiche della parete arteriosa.² Tuttavia, il loro impatto può variare notevolmente tra individui. ",{"type":2208,"children":2241},[2242],{"type":2201,"value":2243},"Questo è il principio dell’invecchiamento vascolare: la data di nascita fornisce un contesto importante, ma non mostra sempre come il sistema vascolare abbia risposto ai rischi accumulati nel tempo. ",{"type":2208,"children":2245},[2246],{"type":2201,"value":2247},"La professoressa Bruno descrive la valutazione della rigidità arteriosa come uno dei modi per valutare l’invecchiamento vascolare. Può fornire informazioni sulle condizioni meccaniche delle arterie e rivelare quando la salute vascolare appare più anziana, o più giovane, di quanto suggerisca la sola età cronologica. ",{"type":2249,"children":2250,"attribution":2255},"blockquote",[2251],{"type":2208,"children":2252},[2253],{"type":2201,"value":2254},"“Non vogliamo considerare tutte le persone giovani come malate. Vogliamo identificare le persone a rischio.” ","Professoressa Rosa Maria Bruno ",{"type":2208,"children":2257},[2258],{"type":2201,"value":2259},"L’obiettivo non è ampliare i test fine a sé stessi, ma riconoscere le persone il cui rischio potrebbe non essere completamente visibile attraverso le misure convenzionali, per considerare prevenzione, follow-up o ulteriori valutazioni al momento giusto. ",{"type":2198,"level":435,"children":2261},[2262,2265],{"type":2201,"marks":2263,"value":2264},[2203],"Cosa può aggiungere la misurazione della rigidità arteriosa",{"type":2201,"value":2206},{"type":2208,"children":2267},[2268],{"type":2201,"value":2269},"La rigidità arteriosa descrive le proprietà meccaniche delle arterie. Le arterie sane si espandono e si rilasciano a ogni battito cardiaco, contribuendo ad attenuare la forza pulsatile generata dal cuore. Quando diventano più rigide, questa funzione si riduce. ",{"type":2208,"children":2271},[2272],{"type":2201,"value":2273},"La velocità dell’onda di polso, o PWV, è uno dei metodi non invasivi più consolidati per misurare la rigidità arteriosa. L’onda di polso viaggia più velocemente in un’arteria rigida che in una più elastica. ",{"type":2208,"children":2275},[2276],{"type":2201,"value":2277},"La PWV carotido-femorale, o cfPWV, è considerata lo standard di riferimento non invasivo per valutare la rigidità aortica.³ Anche la PWV braccio-caviglia, o baPWV, è riconosciuta nelle linee guida ESH 2023 come misura della rigidità arteriosa e marcatore di danno d’organo mediato dall’ipertensione.⁶ ",{"type":2208,"children":2279},[2280],{"type":2201,"value":2281},"La misurazione della rigidità arteriosa non sostituisce la valutazione convenzionale del rischio cardiovascolare. Pressione arteriosa, colesterolo, diabete, fumo, storia familiare e giudizio clinico restano essenziali, ma possono non spiegare completamente il rischio individuale. ",{"item":2165,"type":2229},{"type":2198,"level":435,"children":2284},[2285,2288],{"type":2201,"marks":2286,"value":2287},[2203],"Cosa mostra l’evidenza",{"type":2201,"value":2206},{"type":2208,"children":2290},[2291],{"type":2201,"value":2292},"Il valore clinico della valutazione della rigidità arteriosa è sostenuto da studi prospettici. Sebbene la PWV aortica possa essere misurata invasivamente durante il cateterismo cardiaco, ciò non è pratico nella prevenzione di routine. Il confronto con la cfPWV non invasiva ha mostrato una stretta relazione tra le misure, sostenendo la rilevanza clinica della cfPWV per la valutazione della rigidità aortica.⁷ ",{"type":2208,"children":2294},[2295],{"type":2201,"value":2296},"Una delle più ampie analisi ha combinato dati individuali di 17.635 partecipanti; durante il follow-up, 1.785 hanno avuto un evento cardiovascolare. Una PWV aortica più elevata era associata a un maggior rischio di cardiopatia coronarica, ictus ed eventi cardiovascolari complessivi.⁴ Per ogni aumento di una deviazione standard della PWV aortica log-trasformata, il rischio corretto per età e sesso era maggiore del 35% per cardiopatia coronarica, del 54% per ictus e del 45% per gli eventi cardiovascolari complessivi.⁴ ",{"type":2208,"children":2298},[2299],{"type":2201,"value":2300},"Questi risultati non implicano che la PWV debba essere misurata indiscriminatamente. Mostrano perché la salute arteriosa può offrire una prospettiva aggiuntiva utile quando le informazioni convenzionali lasciano aperta una domanda clinica importante. ",{"type":2198,"level":435,"children":2302},[2303,2306],{"type":2201,"marks":2304,"value":2305},[2203],"La prevenzione è una sfida multidimensionale",{"type":2201,"value":2206},{"type":2208,"children":2308},[2309],{"type":2201,"value":2310},"Pressione arteriosa, colesterolo, glicemia, stile di vita, storia familiare, reperti cardiaci e salute vascolare possono tutti fornire informazioni clinicamente rilevanti. ",{"type":2249,"children":2312,"attribution":2255},[2313],{"type":2208,"children":2314},[2315],{"type":2201,"value":2316},"“La prevenzione cardiovascolare è, per definizione, un problema multidimensionale.” ",{"type":2208,"children":2318},[2319],{"type":2201,"value":2320},"\nLa prevenzione non può quindi basarsi su un singolo numero o un singolo momento. Le linee guida ESC 2024 riconoscono la PWV come modificatore del rischio cardiovascolare da considerare in persone selezionate con pressione elevata quando la decisione terapeutica rimane incerta dopo la valutazione convenzionale.⁵ Le linee guida ESH 2023 identificano cfPWV e baPWV come misure della rigidità delle grandi arterie a supporto della valutazione del rischio e come misure di danno d’organo mediato dall’ipertensione.⁶ ",{"type":2198,"level":435,"children":2322},[2323,2326],{"type":2201,"marks":2324,"value":2325},[2203],"Dalle misurazioni individuali a una visione più connessa",{"type":2201,"value":2206},{"type":2208,"children":2328},[2329],{"type":2201,"value":2330},"Con una prevenzione più proattiva, la diagnostica deve fare più che confermare o escludere una malattia. Deve aiutare a riconoscere pattern, comprendere il rischio individuale e definire il passo successivo più appropriato. ",{"type":2208,"children":2332},[2333],{"type":2201,"value":2334},"Questo richiede che pressione arteriosa, fattori di rischio cardiovascolare, anamnesi e misurazioni arteriose siano disponibili in un flusso clinico strutturato. È il principio dell’Integrated Arterial Assessment: passare da risultati isolati a una visione connessa e clinicamente significativa della salute arteriosa. ",{"type":2198,"level":435,"children":2336},[2337,2340],{"type":2201,"marks":2338,"value":2339},[2203],"Vuoi scoprire come la valutazione della rigidità arteriosa può supportare il tuo flusso di lavoro clinico?",{"type":2201,"value":2206},{"type":2208,"children":2342},[2343],{"type":2201,"value":2344},"I nostri specialisti sono disponibili per rispondere alle tue domande e discutere le opzioni rilevanti per il tuo contesto. ",{"item":2180,"type":2229},{"type":2208,"children":2347},[2348],{"type":2201,"value":48},{"type":2208,"children":2350},[2351,2354],{"type":2201,"marks":2352,"value":2353},[2203],"Letture correlate",{"type":2201,"value":2206},{"type":2356,"style":2357,"children":2358},"list","bulleted",[2359,2377],{"type":2360,"children":2361},"listItem",[2362],{"type":2208,"children":2363},[2364,2376],{"url":2365,"meta":2366,"type":12,"children":2373},"https:\u002F\u002Fmesimedical.com\u002Finsights\u002Fpulse-wave-velocity-the-hidden-marker-of-arterial-age",[2367,2370],{"id":2368,"value":2369},"rel","noreferrer noopener",{"id":2371,"value":2372},"target","_blank",[2374],{"type":2201,"value":2375},"PWV: il marcatore nascosto dell’età arteriosa",{"type":2201,"value":2206},{"type":2360,"children":2378},[2379],{"type":2208,"children":2380},[2381,2389],{"url":2382,"meta":2383,"type":12,"children":2386},"https:\u002F\u002Fmesimedical.com\u002Farterial-assessment",[2384,2385],{"id":2368,"value":2369},{"id":2371,"value":2372},[2387],{"type":2201,"value":2388},"Integrated Arterial Assessment",{"type":2201,"value":2206},{"type":2208,"children":2391},[2392],{"type":2201,"value":48},{"type":2208,"children":2394},[2395],{"type":2201,"value":48},{"type":2208,"children":2397},[2398,2401],{"type":2201,"marks":2399,"value":2400},[2203],"Informazioni sulla professoressa Rosa Maria Bruno",{"type":2201,"value":2206},{"type":2208,"children":2403},[2404],{"type":2201,"value":2405},"La professoressa Rosa Maria Bruno è professoressa all’Université Paris Cité e responsabile dell’unità di farmacologia clinica dell’Hôpital Européen Georges Pompidou di Parigi. Si occupa di ipertensione, invecchiamento vascolare e applicazione clinica della valutazione vascolare non invasiva.",{"type":2208,"children":2407},[2408],{"type":2201,"value":48},{"item":2186,"type":2229},{"type":2208,"children":2411},[2412],{"type":2201,"value":48},{"alt":2155,"url":2414,"width":2415,"height":2416,"responsiveImage":2417},"https:\u002F\u002Fwww.datocms-assets.com\u002F160495\u002F1788505431-mesi_testimonial_rosa-maria-bruno_blog-banner.png",1601,901,{"srcSet":2418,"webpSrcSet":2419,"sizes":2420,"src":2421,"width":2422,"height":950,"aspectRatio":2423,"alt":2155,"title":18,"bgColor":2424,"base64":2425},"https:\u002F\u002Fwww.datocms-assets.com\u002F160495\u002F1788505431-mesi_testimonial_rosa-maria-bruno_blog-banner.png?ar64=MjE6OQ&auto=compress&crop=focalpoint&dpr=0.25&fit=crop&w=1440 360w,https:\u002F\u002Fwww.datocms-assets.com\u002F160495\u002F1788505431-mesi_testimonial_rosa-maria-bruno_blog-banner.png?ar64=MjE6OQ&auto=compress&crop=focalpoint&dpr=0.5&fit=crop&w=1440 720w,https:\u002F\u002Fwww.datocms-assets.com\u002F160495\u002F1788505431-mesi_testimonial_rosa-maria-bruno_blog-banner.png?ar64=MjE6OQ&auto=compress&crop=focalpoint&dpr=0.75&fit=crop&w=1440 1080w,https:\u002F\u002Fwww.datocms-assets.com\u002F160495\u002F1788505431-mesi_testimonial_rosa-maria-bruno_blog-banner.png?ar64=MjE6OQ&auto=compress&crop=focalpoint&fit=crop&w=1440 1440w","https:\u002F\u002Fwww.datocms-assets.com\u002F160495\u002F1788505431-mesi_testimonial_rosa-maria-bruno_blog-banner.png?ar64=MjE6OQ&auto=compress&crop=focalpoint&dpr=0.25&fit=crop&fm=webp&w=1440 360w,https:\u002F\u002Fwww.datocms-assets.com\u002F160495\u002F1788505431-mesi_testimonial_rosa-maria-bruno_blog-banner.png?ar64=MjE6OQ&auto=compress&crop=focalpoint&dpr=0.5&fit=crop&fm=webp&w=1440 720w,https:\u002F\u002Fwww.datocms-assets.com\u002F160495\u002F1788505431-mesi_testimonial_rosa-maria-bruno_blog-banner.png?ar64=MjE6OQ&auto=compress&crop=focalpoint&dpr=0.75&fit=crop&fm=webp&w=1440 1080w,https:\u002F\u002Fwww.datocms-assets.com\u002F160495\u002F1788505431-mesi_testimonial_rosa-maria-bruno_blog-banner.png?ar64=MjE6OQ&auto=compress&crop=focalpoint&fit=crop&fm=webp&w=1440 1440w","(max-width: 1440px) 100vw, 1440px","https:\u002F\u002Fwww.datocms-assets.com\u002F160495\u002F1788505431-mesi_testimonial_rosa-maria-bruno_blog-banner.png?ar64=MjE6OQ&auto=compress&crop=focalpoint&fit=crop&w=1440",1440,2.3338735818476497,"#fad75b","data:image\u002Fjpeg;base64,\u002F9j\u002F4AAQSkZJRgABAQAAAQABAAD\u002F2wCEAAoHBwgHBgoICAgLCgoLDhcNDRIWDh0NEQ0VIx0dGBYVFhUaHysjGikoHSEWJDUlKC0vMjIyGSI4PTcwPCsxMi8BCgsLDg0NEA0NFC8dFhwvLy8vLy8vLy8vLy8vLy8vLy8vLy8vLy8vLy8vLy8vLy8vLy8vLy8vLy8vLy8vLy8vL\u002F\u002FAABEIAAsAGAMBIgACEQEDEQH\u002FxAAYAAACAwAAAAAAAAAAAAAAAAAFBgADB\u002F\u002FEAB4QAAEDBAMAAAAAAAAAAAAAAAEAAgMEBhESEzFB\u002F8QAFQEBAQAAAAAAAAAAAAAAAAAAAgH\u002FxAAUEQEAAAAAAAAAAAAAAAAAAAAA\u002F9oADAMBAAIRAxEAPwDWTUBzwg1yV8LINSQr9jntJd4yyAjDiiRrtqsi48j1RArQc404yVFUf\u002F\u002FZ",{"left":2037,"top":2037,"width":2038,"height":2038,"rotate":2037,"vFlip":68,"hFlip":68,"body":2427},"\u003Cg fill=\"none\">\u003Cg id=\"play\">\n\u003Cpath id=\"Vector\" d=\"M17.5956 11.4481L9.71626 6.62959C9.61671 6.56783 9.50235 6.53407 9.38522 6.53185C9.26809 6.52964 9.15253 6.55906 9.05071 6.61701C8.94964 6.67256 8.86544 6.75437 8.80701 6.8538C8.74859 6.95324 8.71809 7.0666 8.71876 7.18193V16.819C8.71809 16.9343 8.74859 17.0477 8.80701 17.1471C8.86544 17.2465 8.94964 17.3283 9.05071 17.3839C9.15253 17.4418 9.26809 17.4713 9.38522 17.469C9.50235 17.4668 9.61671 17.4331 9.71626 17.3713L17.5956 12.5528C17.6905 12.4951 17.7689 12.414 17.8233 12.3173C17.8777 12.2206 17.9062 12.1114 17.9062 12.0004C17.9062 11.8895 17.8777 11.7803 17.8233 11.6836C17.7689 11.5869 17.6905 11.5058 17.5956 11.4481Z\" fill=\"currentColor\"\u002F>\n\u003C\u002Fg>\u003C\u002Fg>",{"left":2037,"top":2037,"width":2038,"height":2038,"rotate":2037,"vFlip":68,"hFlip":68,"body":2429},"\u003Cg fill=\"none\">\u003Cg id=\"arrow-down\">\n\u003Cpath id=\"Vector\" d=\"M19.281 14.0306L12.531 20.7806C12.4614 20.8504 12.3787 20.9057 12.2876 20.9434C12.1966 20.9812 12.099 21.0006 12.0004 21.0006C11.9019 21.0006 11.8043 20.9812 11.7132 20.9434C11.6222 20.9057 11.5394 20.8504 11.4698 20.7806L4.71979 14.0306C4.57906 13.8899 4.5 13.699 4.5 13.5C4.5 13.301 4.57906 13.1101 4.71979 12.9694C4.86052 12.8286 5.05139 12.7496 5.25042 12.7496C5.44944 12.7496 5.64031 12.8286 5.78104 12.9694L11.2504 18.4397V3.75C11.2504 3.55109 11.3294 3.36032 11.4701 3.21967C11.6107 3.07902 11.8015 3 12.0004 3C12.1993 3 12.3901 3.07902 12.5307 3.21967C12.6714 3.36032 12.7504 3.55109 12.7504 3.75V18.4397L18.2198 12.9694C18.3605 12.8286 18.5514 12.7496 18.7504 12.7496C18.9494 12.7496 19.1403 12.8286 19.281 12.9694C19.4218 13.1101 19.5008 13.301 19.5008 13.5C19.5008 13.699 19.4218 13.8899 19.281 14.0306Z\" fill=\"currentColor\"\u002F>\n\u003C\u002Fg>\u003C\u002Fg>",1792751040889]