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v2","test-v2",[1812,1813,1814,1815,1816,1817,1818,1819,1820,1821],{"__typename":73,"id":72,"title":67,"slug":75},{"__typename":73,"id":84,"title":80,"slug":85},{"__typename":73,"id":93,"title":89,"slug":94},{"__typename":73,"id":102,"title":98,"slug":103},{"__typename":73,"id":111,"title":107,"slug":112},{"__typename":73,"id":131,"title":133,"slug":132},{"__typename":73,"id":566,"title":568,"slug":567},{"__typename":73,"id":557,"title":553,"slug":558},{"__typename":73,"id":576,"title":572,"slug":577},{"__typename":73,"id":585,"title":581,"slug":586},{"__typename":1823,"id":1824,"text":1825,"active":68,"link":18},"PromoBannerRecord","IZN2vWtySLe3lCbELb1Rfw","\u003Cp>Placerat tortor massa aenean diam elementum risus facilisis sed eget elementum vestibulum ut.\u003C\u002Fp>",[1827,1840,1856,1870,1887,1904,1914,1928,1942,1956,1970,1979,1992,2007,2020],{"id":1828,"__typename":1829,"_modelApiKey":1830,"title":148,"media":1831,"description":1833,"reference":1834,"category":1835},"Mc_O5HIMSxi-WJWg9zWgTQ","PageLinkRecord","page_link",{"alt":151,"url":152,"width":153,"height":154,"responsiveImage":1832},{"srcSet":156,"webpSrcSet":157,"sizes":158,"src":159,"width":160,"height":161,"aspectRatio":162,"alt":151,"title":151,"bgColor":163,"base64":164},"\u003Cp>\u003Cspan data-olk-copy-source=\"MessageBody\">Examens rapides, dossiers instantanés, plus de temps pour vos patients.\u003C\u002Fspan>\u003C\u002Fp>",{"id":167,"__typename":44,"_modelApiKey":45,"slug":168,"title":169},{"__typename":1836,"id":1837,"name":1838,"slug":1839},"SpecialityCategoryRecord","ThcnPekuQbCQz_fv8O3SxA","Doctor’s practice","doctor-s-practice",{"id":1841,"__typename":1829,"_modelApiKey":1830,"title":1842,"media":1843,"description":1853,"reference":1854,"category":1855},"UbP8NN0KTf6zMJRnBnBgvw","Médecine générale",{"alt":1844,"url":1845,"width":1846,"height":1846,"responsiveImage":1847},"MESI mTABLET for Primary care","https:\u002F\u002Fwww.datocms-assets.com\u002F160495\u002F1759468929-primary-care-1080-1080.png",4500,{"srcSet":1848,"webpSrcSet":1849,"sizes":158,"src":1850,"width":160,"height":160,"aspectRatio":76,"alt":1844,"title":1844,"bgColor":1851,"base64":1852},"https:\u002F\u002Fwww.datocms-assets.com\u002F160495\u002F1759468929-primary-care-1080-1080.png?auto=compress&crop=focalpoint&dpr=0.25&fit=crop&w=1080 270w,https:\u002F\u002Fwww.datocms-assets.com\u002F160495\u002F1759468929-primary-care-1080-1080.png?auto=compress&crop=focalpoint&dpr=0.5&fit=crop&w=1080 540w,https:\u002F\u002Fwww.datocms-assets.com\u002F160495\u002F1759468929-primary-care-1080-1080.png?auto=compress&crop=focalpoint&dpr=0.75&fit=crop&w=1080 810w,https:\u002F\u002Fwww.datocms-assets.com\u002F160495\u002F1759468929-primary-care-1080-1080.png?auto=compress&crop=focalpoint&fit=crop&w=1080 1080w,https:\u002F\u002Fwww.datocms-assets.com\u002F160495\u002F1759468929-primary-care-1080-1080.png?auto=compress&crop=focalpoint&dpr=1.5&fit=crop&w=1080 1620w,https:\u002F\u002Fwww.datocms-assets.com\u002F160495\u002F1759468929-primary-care-1080-1080.png?auto=compress&crop=focalpoint&dpr=2&fit=crop&w=1080 2160w,https:\u002F\u002Fwww.datocms-assets.com\u002F160495\u002F1759468929-primary-care-1080-1080.png?auto=compress&crop=focalpoint&dpr=3&fit=crop&w=1080 3240w,https:\u002F\u002Fwww.datocms-assets.com\u002F160495\u002F1759468929-primary-care-1080-1080.png?auto=compress&crop=focalpoint&dpr=4&fit=crop&w=1080 4320w","https:\u002F\u002Fwww.datocms-assets.com\u002F160495\u002F1759468929-primary-care-1080-1080.png?auto=compress&crop=focalpoint&dpr=0.25&fit=crop&fm=webp&w=1080 270w,https:\u002F\u002Fwww.datocms-assets.com\u002F160495\u002F1759468929-primary-care-1080-1080.png?auto=compress&crop=focalpoint&dpr=0.5&fit=crop&fm=webp&w=1080 540w,https:\u002F\u002Fwww.datocms-assets.com\u002F160495\u002F1759468929-primary-care-1080-1080.png?auto=compress&crop=focalpoint&dpr=0.75&fit=crop&fm=webp&w=1080 810w,https:\u002F\u002Fwww.datocms-assets.com\u002F160495\u002F1759468929-primary-care-1080-1080.png?auto=compress&crop=focalpoint&fit=crop&fm=webp&w=1080 1080w,https:\u002F\u002Fwww.datocms-assets.com\u002F160495\u002F1759468929-primary-care-1080-1080.png?auto=compress&crop=focalpoint&dpr=1.5&fit=crop&fm=webp&w=1080 1620w,https:\u002F\u002Fwww.datocms-assets.com\u002F160495\u002F1759468929-primary-care-1080-1080.png?auto=compress&crop=focalpoint&dpr=2&fit=crop&fm=webp&w=1080 2160w,https:\u002F\u002Fwww.datocms-assets.com\u002F160495\u002F1759468929-primary-care-1080-1080.png?auto=compress&crop=focalpoint&dpr=3&fit=crop&fm=webp&w=1080 3240w,https:\u002F\u002Fwww.datocms-assets.com\u002F160495\u002F1759468929-primary-care-1080-1080.png?auto=compress&crop=focalpoint&dpr=4&fit=crop&fm=webp&w=1080 4320w","https:\u002F\u002Fwww.datocms-assets.com\u002F160495\u002F1759468929-primary-care-1080-1080.png?auto=compress&crop=focalpoint&fit=crop&w=1080","#9dbe4b","data:image\u002Fjpeg;base64,\u002F9j\u002F4AAQSkZJRgABAQAAAQABAAD\u002F2wCEAAoHBwgHBgoIEggTFhAVDiQaDg0ODhUNDw4OIR8ZGBYVIhUdHysjGikoKSEWJDUlKC0vMjIyGSI4PTcwPCsxMi8BCgsLDg0PHA0QHC8oFhwvLy8vLy8vLy8vLy8vLy8vLy8vLy8vLy8vLy8vLy8vLy8vLy8vLy8vLy8vLy8vLy8vL\u002F\u002FAABEIABgAGAMBIgACEQEDEQH\u002FxAAZAAEBAAMBAAAAAAAAAAAAAAAABAEFBwP\u002FxAAfEAABAwQDAQAAAAAAAAAAAAABAAIDBAURQRMUIRL\u002FxAAXAQADAQAAAAAAAAAAAAAAAAAAAQIE\u002F8QAGBEBAQEBAQAAAAAAAAAAAAAAAAECEhH\u002F2gAMAwEAAhEDEQA\u002FAOsz1DWVAGVjnY0l2dKK4QvFYPV6tpS6M+6UatU18V5jiuThlFLFZOW5uP1tEvaF9yrT3AFkVkmMZ0iLRrMJNRVEvfJyiIjmB\u002F\u002FZ","\u003Cp>Optimisez votre flux de travail quotidien et soignez plus de patients en moins de temps grâce au MESI mTABLET - des diagnostics intelligents conçus pour les établissements de soins primaires très occupés.\u003C\u002Fp>",{"id":221,"__typename":44,"_modelApiKey":45,"slug":222,"title":223},{"__typename":1836,"id":1837,"name":1838,"slug":1839},{"id":1857,"__typename":1829,"_modelApiKey":1830,"title":602,"media":1858,"description":1867,"reference":1868,"category":1869},"U7D5H1iEREmkDO6M8pKgFg",{"alt":1859,"url":1860,"width":1846,"height":1846,"responsiveImage":1861},"MESI mTABLET for Nurse practice","https:\u002F\u002Fwww.datocms-assets.com\u002F160495\u002F1759468929-nurse-practices-1080-1080.png",{"srcSet":1862,"webpSrcSet":1863,"sizes":158,"src":1864,"width":160,"height":160,"aspectRatio":76,"alt":1859,"title":1859,"bgColor":1865,"base64":1866},"https:\u002F\u002Fwww.datocms-assets.com\u002F160495\u002F1759468929-nurse-practices-1080-1080.png?auto=compress&crop=focalpoint&dpr=0.25&fit=crop&w=1080 270w,https:\u002F\u002Fwww.datocms-assets.com\u002F160495\u002F1759468929-nurse-practices-1080-1080.png?auto=compress&crop=focalpoint&dpr=0.5&fit=crop&w=1080 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hôpitaux et les cliniques sont confrontés à une dure réalité : plus de patients, moins de personnel et des outils fragmentés qui ralentissent la prise de décision. 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Interview de la professeure Rosa Maria Bruno",{"__typename":2157,"_modelApiKey":268,"title":2070,"subtitle":48,"videoUrl":2158,"thumbnail":2159},"VideoRecord","https:\u002F\u002Fplayer.vimeo.com\u002Fprogressive_redirect\u002Fplayback\u002F1221751262\u002Frendition\u002F720p\u002Ffile.mp4%20%28720p%29.mp4?loc=external&log_user=0&signature=70fa8662f06ff61f70d2651aeeb2a0c4aa19a84e373f359618eb96aab54acb97",{"title":18,"customData":2160,"url":2161,"width":527,"height":160,"alt":2162,"mimeType":529,"format":530,"responsiveImage":2163},{},"https:\u002F\u002Fwww.datocms-assets.com\u002F160495\u002F1788503735-thumb.jpg","Rosa Maria Bruno",{"srcSet":2164,"webpSrcSet":2165,"sizes":2166,"src":2167,"width":527,"height":160,"aspectRatio":2168,"alt":2162,"title":18,"bgColor":2169,"base64":2170},"https:\u002F\u002Fwww.datocms-assets.com\u002F160495\u002F1788503735-thumb.jpg?auto=compress&crop=focalpoint&dpr=0.25&fit=crop 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256w,https:\u002F\u002Fwww.datocms-assets.com\u002F160495\u002F1788504291-rosa-maria-bruno.jpg?dpr=0.5 512w,https:\u002F\u002Fwww.datocms-assets.com\u002F160495\u002F1788504291-rosa-maria-bruno.jpg?dpr=0.75 768w,https:\u002F\u002Fwww.datocms-assets.com\u002F160495\u002F1788504291-rosa-maria-bruno.jpg 1024w","https:\u002F\u002Fwww.datocms-assets.com\u002F160495\u002F1788504291-rosa-maria-bruno.jpg?dpr=0.25&fm=webp 256w,https:\u002F\u002Fwww.datocms-assets.com\u002F160495\u002F1788504291-rosa-maria-bruno.jpg?dpr=0.5&fm=webp 512w,https:\u002F\u002Fwww.datocms-assets.com\u002F160495\u002F1788504291-rosa-maria-bruno.jpg?dpr=0.75&fm=webp 768w,https:\u002F\u002Fwww.datocms-assets.com\u002F160495\u002F1788504291-rosa-maria-bruno.jpg?fm=webp 1024w","(max-width: 1024px) 100vw, 1024px",1.499267935578331,"#e1a851","data:image\u002Fjpeg;base64,\u002F9j\u002F4AAQSkZJRgABAQAAAQABAAD\u002F2wCEAAoHBwgHBgoICAgXCgoLDhgQFg0NFR0OFhYVIx8ZGBYfFhYdHysjGh0oHSEWJDUlKC0vMjIyGSI4PTcwPCsxMi8BCgsLDg0OHBAJHDAcFigvLy8vLy8vLy8vLy8vNTUvLy8vLy81Ly8vLy8vLy8vLy8vLy8vLy8vLy8vLy8vLy8vL\u002F\u002FAABEIABEAGAMBIgACEQEDEQH\u002FxAAZAAEAAwEBAAAAAAAAAAAAAAAAAwYHBAH\u002FxAAhEAABAwQCAwEAAAAAAAAAAAAAAQIDBAURMQYhMzRRB\u002F\u002FEABYBAQEBAAAAAAAAAAAAAAAAAAECAP\u002FEABgRAQEAAwAAAAAAAAAAAAAAAAABAgMR\u002F9oADAMBAAIRAxEAPwDj5urKq6Mei6U9SFJaaFGrrBVrtdJJ8SZ7JKG8TpE1VXRWdvUxvfFkc2zRt+Ar3Ar7JV06RO7QAWI1fiJKP1wB2CNT\u002FM9gAIz\u002F2Q==",{"id":2187,"_modelApiKey":2188,"__typename":2189,"externalLink":2190,"recordLink":18,"primary":49,"title":2191},"TPT46bILQE6pM7m319EaKA","cta","CtaRecord","https:\u002F\u002Fmesimedical.com\u002Fes\u002Fcontacte-a-ventas","Demander plus d’informations",{"id":2193,"_modelApiKey":2194,"__typename":2195,"title":2196,"html":2197},"B_kjzDhlR6ieufGbhQTz0g","resource","ResourceRecord","Références","\u003Col style=\"margin-top: 0cm;\" start=\"1\" type=\"1\">\n\u003Cli class=\"MsoNormal\" style=\"mso-list: l1 level1 lfo1; tab-stops: list 36.0pt;\">World Health Organization Regional Office for Europe, ‘Cardiovascular diseases’, 17 July 2024, \u003Cb>Key facts\u003C\u002Fb>. Available at: \u003Ca href=\"https:\u002F\u002Fwww.who.int\u002Feurope\u002Fnews-room\u002Ffact-sheets\u002Fitem\u002Fcardiovascular-diseases\" target=\"_blank\" rel=\"noopener\">https:\u002F\u002Fwww.who.int\u002Feurope\u002Fnews-room\u002Ffact-sheets\u002Fitem\u002Fcardiovascular-diseases\u003C\u002Fa> (Accessed: 2 September 2026). \u003Co:p>\u003C\u002Fo:p>\u003C\u002Fli>\n\u003C\u002Fol>\n\u003Col style=\"margin-top: 0cm;\" start=\"2\" type=\"1\">\n\u003Cli class=\"MsoNormal\" style=\"mso-list: l4 level1 lfo2; tab-stops: list 36.0pt;\">Boutouyrie, P. and Bruno, R.-M., ‘The Clinical Significance and Application of Vascular Stiffness Measurements’, \u003Ci>American Journal of Hypertension\u003C\u002Fi>, 32.1 (2019), pp. 4–11. Available at: \u003Ca href=\"https:\u002F\u002Fdoi.org\u002F10.1093\u002Fajh\u002Fhpy145\" target=\"_blank\" rel=\"noopener\">https:\u002F\u002Fdoi.org\u002F10.1093\u002Fajh\u002Fhpy145\u003C\u002Fa> (Accessed: 2 September 2026). \u003Co:p>\u003C\u002Fo:p>\u003C\u002Fli>\n\u003C\u002Fol>\n\u003Col style=\"margin-top: 0cm;\" start=\"3\" type=\"1\">\n\u003Cli class=\"MsoNormal\" style=\"mso-list: l0 level1 lfo3; tab-stops: list 36.0pt;\">Van Bortel, L. M., Laurent, S., Boutouyrie, P., Chowienczyk, P., Cruickshank, J. K., De Backer, T. \u003Ci>et al.\u003C\u002Fi>, ‘Expert Consensus Document on the Measurement of Aortic Stiffness in Daily Practice Using Carotid-Femoral Pulse Wave Velocity’, \u003Ci>Journal of Hypertension\u003C\u002Fi>, 30.3 (2012), pp. 445–448. Available at: \u003Ca href=\"https:\u002F\u002Fdoi.org\u002F10.1097\u002FHJH.0b013e32834fa8b0\" target=\"_blank\" rel=\"noopener\">https:\u002F\u002Fdoi.org\u002F10.1097\u002FHJH.0b013e32834fa8b0\u003C\u002Fa> (Accessed: 2 September 2026). \u003Co:p>\u003C\u002Fo:p>\u003C\u002Fli>\n\u003C\u002Fol>\n\u003Col style=\"margin-top: 0cm;\" start=\"4\" type=\"1\">\n\u003Cli class=\"MsoNormal\" style=\"mso-list: l5 level1 lfo4; tab-stops: list 36.0pt;\">Ben-Shlomo, Y., Spears, M., Boustred, C., May, M., Anderson, S. G., Benjamin, E. J., Boutouyrie, P. \u003Ci>et al.\u003C\u002Fi>, ‘Aortic Pulse Wave Velocity Improves Cardiovascular Event Prediction: An Individual Participant Meta-Analysis of Prospective Observational Data from 17,635 Subjects’, \u003Ci>Journal of the American College of Cardiology\u003C\u002Fi>, 63.7 (2014), pp. 636–646. Available at: \u003Ca href=\"https:\u002F\u002Fdoi.org\u002F10.1016\u002Fj.jacc.2013.09.063\" target=\"_blank\" rel=\"noopener\">https:\u002F\u002Fdoi.org\u002F10.1016\u002Fj.jacc.2013.09.063\u003C\u002Fa> (Accessed: 2 September 2026). \u003Co:p>\u003C\u002Fo:p>\u003C\u002Fli>\n\u003C\u002Fol>\n\u003Col style=\"margin-top: 0cm;\" start=\"5\" type=\"1\">\n\u003Cli class=\"MsoNormal\" style=\"mso-list: l6 level1 lfo5; tab-stops: list 36.0pt;\">McEvoy, J. W., McCarthy, C. P., Bruno, R. M., Brouwers, S., Canavan, M. D., Ceconi, C. \u003Ci>et al.\u003C\u002Fi>, ‘2024 ESC Guidelines for the Management of Elevated Blood Pressure and Hypertension’, \u003Ci>European Heart Journal\u003C\u002Fi>, 45.38 (2024), pp. 3912–4018, especially section 6.4.3 and Recommendation Table 4. Available at: \u003Ca href=\"https:\u002F\u002Fdoi.org\u002F10.1093\u002Feurheartj\u002Fehae178\" target=\"_blank\" rel=\"noopener\">https:\u002F\u002Fdoi.org\u002F10.1093\u002Feurheartj\u002Fehae178\u003C\u002Fa> (Accessed: 2 September 2026). \u003Co:p>\u003C\u002Fo:p>\u003C\u002Fli>\n\u003C\u002Fol>\n\u003Col style=\"margin-top: 0cm;\" start=\"6\" type=\"1\">\n\u003Cli class=\"MsoNormal\" style=\"mso-list: l3 level1 lfo6; tab-stops: list 36.0pt;\">Mancia, G., Kreutz, R., Brunström, M., Burnier, M., Grassi, G., Januszewicz, A. \u003Ci>et al.\u003C\u002Fi>, ‘2023 ESH Guidelines for the Management of Arterial Hypertension’, \u003Ci>Journal of Hypertension\u003C\u002Fi>, 41.12 (2023), pp. 1874–2071, especially section 5.5.2.2 and Table 11. Available at: \u003Ca href=\"https:\u002F\u002Fdoi.org\u002F10.1097\u002FHJH.0000000000003480\" target=\"_blank\" rel=\"noopener\">https:\u002F\u002Fdoi.org\u002F10.1097\u002FHJH.0000000000003480\u003C\u002Fa> (Accessed: 2 September 2026). \u003Co:p>\u003C\u002Fo:p>\u003C\u002Fli>\n\u003C\u002Fol>\n\u003Col style=\"margin-top: 0cm;\" start=\"7\" type=\"1\">\n\u003Cli class=\"MsoNormal\" style=\"mso-list: l2 level1 lfo7; tab-stops: list 36.0pt;\">Podolec, P., Kopeć, G., Podolec, J., Wilkołek, P., Krochin, M., Rubiś, P. \u003Ci>et al.\u003C\u002Fi>, ‘Aortic Pulse Wave Velocity and Carotid-Femoral Pulse Wave Velocity: Similarities and Discrepancies’, \u003Ci>Hypertension Research\u003C\u002Fi>, 30.12 (2007), pp. 1151–1158. Available at: \u003Ca href=\"https:\u002F\u002Fdoi.org\u002F10.1291\u002Fhypres.30.1151\" target=\"_blank\" rel=\"noopener\">https:\u002F\u002Fdoi.org\u002F10.1291\u002Fhypres.30.1151\u003C\u002Fa> (Accessed: 2 September 2026). \u003Co:p>\u003C\u002Fo:p>\u003C\u002Fli>\n\u003C\u002Fol>",[],{"schema":2200,"document":2201},"dast",{"type":2202,"children":2203},"root",[2204,2214,2219,2223,2227,2231,2235,2238,2240,2243,2249,2253,2257,2261,2265,2273,2277,2283,2287,2291,2295,2299,2302,2303,2309,2313,2317,2321,2325,2329,2333,2339,2343,2349,2353,2357,2361,2365,2371,2375,2379,2383,2387,2393,2397,2398,2404,2439,2442,2445,2451,2455,2458,2459],{"type":2205,"level":445,"children":2206},"heading",[2207,2212],{"type":2208,"marks":2209,"value":2211},"span",[2210],"strong","La professeure Rosa Maria Bruno sur le vieillissement vasculaire, la prévention et l’identification précoce des personnes nécessitant une attention particulière",{"type":2208,"value":2213}," ",{"type":2215,"children":2216},"paragraph",[2217],{"type":2208,"value":2218},"Dans la prévention cardiovasculaire, l’âge est l’un des facteurs les plus déterminants pour évaluer le risque. C’est aussi l’une des raisons pour lesquelles les changements précoces peuvent être difficiles à reconnaître. ",{"type":2215,"children":2220},[2221],{"type":2208,"value":2222},"Une personne plus jeune peut présenter un faible risque cardiovasculaire calculé à court terme, alors que ses artères ont déjà commencé à subir les effets cumulés d’une pression artérielle élevée, de facteurs métaboliques, du mode de vie ou d’autres expositions. De même, deux personnes du même âge présentant des mesures similaires peuvent ne pas avoir la même santé vasculaire. ",{"type":2215,"children":2224},[2225],{"type":2208,"value":2226},"Cette question est importante partout en Europe. Les maladies cardiovasculaires restent la première cause de décès et de handicap dans l'europe selon l’OMS. En 2019, elles ont causé environ 4,2 millions de décès, soit 42,5 % de l’ensemble des décès.¹ ",{"type":2215,"children":2228},[2229],{"type":2208,"value":2230},"La prévention ne consiste donc pas uniquement à réagir à une maladie déjà établie. Elle consiste aussi à identifier les personnes dont le risque mérite une attention avant l’apparition de symptômes ou d’événements aigus. ",{"type":2215,"children":2232},[2233],{"type":2208,"value":2234},"Cette question était au cœur de la présentation de la professeure Rosa Maria Bruno lors de la MESI Conference 2026. Professeure à l’Université Paris Cité et responsable de l’unité de pharmacologie clinique de l’Hôpital Européen Georges Pompidou à Paris, ses travaux portent sur le vieillissement vasculaire et sur la manière dont une évaluation non invasive peut aider à identifier les personnes dont le risque ne ressort pas toujours des mesures conventionnelles. ",{"type":2215,"children":2236},[2237],{"type":2208,"value":48},{"item":2152,"type":2239},"block",{"type":2215,"children":2241},[2242],{"type":2208,"value":48},{"type":2205,"level":445,"children":2244},[2245,2248],{"type":2208,"marks":2246,"value":2247},[2210],"L’âge chronologique ne raconte pas toute l’histoire",{"type":2208,"value":2213},{"type":2215,"children":2250},[2251],{"type":2208,"value":2252},"Les artères ne vieillissent pas toutes au même rythme. ",{"type":2215,"children":2254},[2255],{"type":2208,"value":2256},"L’hypertension, le diabète, la maladie rénale chronique, le tabagisme et d’autres facteurs de risque cardiovasculaire à long terme peuvent accélérer les changements de la paroi artérielle.² Pourtant, leur impact peut varier considérablement d’une personne à l’autre. ",{"type":2215,"children":2258},[2259],{"type":2208,"value":2260},"C’est le principe du vieillissement vasculaire. La date de naissance apporte un contexte important, mais elle ne montre pas toujours comment le système vasculaire a réagi aux risques accumulés au fil du temps. ",{"type":2215,"children":2262},[2263],{"type":2208,"value":2264},"La professeure Bruno décrit l’évaluation de la rigidité artérielle comme une manière d’évaluer le vieillissement vasculaire. Elle peut renseigner sur l’état mécanique des artères et indiquer si la santé vasculaire paraît plus âgée, ou plus jeune, que ne le suggère l’âge chronologique seul. ",{"type":2266,"children":2267,"attribution":2272},"blockquote",[2268],{"type":2215,"children":2269},[2270],{"type":2208,"value":2271},"« Nous ne voulons pas considérer tous les jeunes comme malades. Nous voulons identifier les personnes à risque. » ","Professeure Rosa Maria Bruno ",{"type":2215,"children":2274},[2275],{"type":2208,"value":2276},"L’objectif n’est pas d’élargir les examens pour le principe. Il est de reconnaître les personnes dont le risque n’est peut-être pas entièrement visible avec les mesures conventionnelles, afin d’envisager au bon moment la prévention, le suivi ou une évaluation complémentaire. ",{"type":2205,"level":445,"children":2278},[2279,2282],{"type":2208,"marks":2280,"value":2281},[2210],"Ce que peut apporter la mesure de la rigidité artérielle",{"type":2208,"value":2213},{"type":2215,"children":2284},[2285],{"type":2208,"value":2286},"La rigidité artérielle décrit les propriétés mécaniques des artères. Des artères saines se dilatent et se rétractent à chaque battement cardiaque, ce qui contribue à amortir la force pulsatile générée par le cœur. Lorsque les artères deviennent plus rigides, cette fonction d’amortissement diminue. ",{"type":2215,"children":2288},[2289],{"type":2208,"value":2290},"La vitesse de l’onde de pouls, ou VOP, est l’une des méthodes non invasives les plus établies pour mesurer la rigidité artérielle. Le principe est simple : l’onde de pouls se déplace plus rapidement dans une artère rigide que dans une artère plus élastique. ",{"type":2215,"children":2292},[2293],{"type":2208,"value":2294},"La VOP carotido-fémorale, ou VOPcf, est considérée comme la méthode de référence non invasive pour l’évaluation de la rigidité aortique.³ La VOP brachiale-cheville, ou VOPbc, est également reconnue dans les recommandations ESH 2023 comme une mesure de la rigidité artérielle et un marqueur d’atteinte d’organe médiée par l’hypertension.⁶ ",{"type":2215,"children":2296},[2297],{"type":2208,"value":2298},"La mesure de la rigidité artérielle ne remplace pas l’évaluation conventionnelle du risque cardiovasculaire. La pression artérielle, le cholestérol, le statut diabétique, le tabagisme, les antécédents familiaux et le jugement clinique restent essentiels. Elle peut toutefois apporter un contexte clinique lorsque ces facteurs n’expliquent pas entièrement le risque individuel. ",{"type":2215,"children":2300},[2301],{"type":2208,"value":48},{"item":2172,"type":2239},{"type":2205,"level":445,"children":2304},[2305,2308],{"type":2208,"marks":2306,"value":2307},[2210],"Ce que montrent les données",{"type":2208,"value":2213},{"type":2215,"children":2310},[2311],{"type":2208,"value":2312},"La valeur clinique de l’évaluation de la rigidité artérielle est étayée par des études prospectives. ",{"type":2215,"children":2314},[2315],{"type":2208,"value":2316},"Bien que la VOP aortique puisse être mesurée de manière invasive lors d’un cathétérisme cardiaque, cette méthode n’est pas adaptée à la prévention de routine. Des données comparant la VOP aortique invasive et la VOPcf non invasive ont montré une relation étroite entre les deux mesures, ce qui soutient la pertinence clinique de la VOPcf comme méthode non invasive d’évaluation de la rigidité aortique.⁷ ",{"type":2215,"children":2318},[2319],{"type":2208,"value":2320},"L’une des plus grandes analyses a combiné les données individuelles de 17 635 participants. Au cours du suivi, 1 785 participants ont présenté un événement cardiovasculaire. Une VOP aortique plus élevée était associée à un risque accru de maladie coronarienne, d’accident vasculaire cérébral et d’événements cardiovasculaires dans leur ensemble.⁴ ",{"type":2215,"children":2322},[2323],{"type":2208,"value":2324},"Pour chaque augmentation d’un écart-type de la VOP aortique transformée logarithmiquement, le risque ajusté pour l’âge et le sexe était supérieur de 35 % pour la maladie coronarienne, de 54 % pour l’AVC et de 45 % pour l’ensemble des événements cardiovasculaires.⁴ ",{"type":2215,"children":2326},[2327],{"type":2208,"value":2328},"L’analyse a également montré que la VOP aortique apportait une information pronostique au-delà des facteurs de risque cardiovasculaire conventionnels. Son intérêt pour améliorer la classification du risque était particulièrement pertinent chez certaines personnes à risque intermédiaire, tandis que l’association relative avec les événements cardiovasculaires était plus forte chez les personnes plus jeunes.⁴ ",{"type":2215,"children":2330},[2331],{"type":2208,"value":2332},"Ces résultats ne signifient pas que la VOP devrait être mesurée sans discernement. Ils montrent pourquoi la santé artérielle peut apporter une perspective complémentaire utile lorsque les informations conventionnelles laissent une question clinique importante sans réponse. ",{"type":2205,"level":445,"children":2334},[2335,2338],{"type":2208,"marks":2336,"value":2337},[2210],"La prévention est un défi multidimensionnel",{"type":2208,"value":2213},{"type":2215,"children":2340},[2341],{"type":2208,"value":2342},"Le risque cardiovasculaire est façonné par plusieurs facteurs. Pression artérielle, cholestérol, glycémie, mode de vie, antécédents familiaux, résultats cardiaques et santé vasculaire peuvent tous fournir des informations cliniques pertinentes. ",{"type":2266,"children":2344,"attribution":2272},[2345],{"type":2215,"children":2346},[2347],{"type":2208,"value":2348},"« La prévention cardiovasculaire est, par définition, un problème multidimensionnel. » ",{"type":2215,"children":2350},[2351],{"type":2208,"value":2352},"La prévention ne peut donc pas reposer sur un seul chiffre ou un seul moment. Le défi pour les professionnels de santé est d’interpréter les informations pertinentes dans leur contexte et de comprendre ce qu’elles signifient pour chaque patient. ",{"type":2215,"children":2354},[2355],{"type":2208,"value":2356},"Les recommandations 2024 de la Société européenne de cardiologie reconnaissent la VOP comme un modificateur du risque cardiovasculaire qui peut être envisagé chez certaines personnes présentant une pression artérielle élevée lorsque la décision d’un traitement antihypertenseur reste incertaine après l’évaluation conventionnelle du risque.⁵ ",{"type":2215,"children":2358},[2359],{"type":2208,"value":2360},"Les recommandations 2023 de la Société européenne d’hypertension identifient la VOPcf et la VOPbc comme des mesures de la rigidité des grandes artères pouvant soutenir l’évaluation du risque cardiovasculaire. Toutes deux figurent parmi les mesures d’atteinte d’organe médiée par l’hypertension.⁶ ",{"type":2215,"children":2362},[2363],{"type":2208,"value":2364},"Ces recommandations soutiennent un rôle clinique ciblé de la mesure de la VOP : non pas comme un outil de dépistage universel, mais comme une information complémentaire lorsque le résultat peut influencer la classification du risque, le suivi ou la prise en charge. ",{"type":2205,"level":445,"children":2366},[2367,2370],{"type":2208,"marks":2368,"value":2369},[2210],"Des mesures individuelles à une vision plus connectée",{"type":2208,"value":2213},{"type":2215,"children":2372},[2373],{"type":2208,"value":2374},"À mesure que la prévention devient plus proactive, le diagnostic doit apporter plus que la confirmation ou l’exclusion d’une maladie. Il doit aider les professionnels de santé à identifier des profils, à comprendre le risque individuel et à déterminer l’étape suivante la plus appropriée. ",{"type":2215,"children":2376},[2377],{"type":2208,"value":2378},"Cela suppose que les informations diagnostiques pertinentes soient disponibles dans un parcours clinique structuré. La pression artérielle, les facteurs de risque cardiovasculaire, les antécédents médicaux et les mesures artérielles peuvent chacun contribuer à une compréhension plus large de la santé vasculaire lorsqu’ils sont considérés ensemble. ",{"type":2215,"children":2380},[2381],{"type":2208,"value":2382},"C’est le principe de l’évaluation artérielle intégrée : passer de résultats isolés à une vision connectée et cliniquement pertinente de la santé artérielle. ",{"type":2215,"children":2384},[2385],{"type":2208,"value":2386},"L’objectif n’est pas de remplacer le jugement clinique ni de prendre des décisions par la technologie seule. Il est d’aider les professionnels de santé à réunir des informations diagnostiques objectives, à les interpréter dans leur contexte et à déterminer l’étape suivante la plus appropriée pour le patient. ",{"type":2205,"level":445,"children":2388},[2389,2392],{"type":2208,"marks":2390,"value":2391},[2210],"Souhaitez-vous découvrir comment l’évaluation de la rigidité artérielle pourrait soutenir votre pratique clinique ?",{"type":2208,"value":2213},{"type":2215,"children":2394},[2395],{"type":2208,"value":2396},"Nos spécialistes sont à votre disposition pour répondre à vos questions et discuter des options pertinentes dans votre contexte. ",{"item":2187,"type":2239},{"type":2215,"children":2399},[2400,2403],{"type":2208,"marks":2401,"value":2402},[2210],"À lire également",{"type":2208,"value":2213},{"type":2405,"style":2406,"children":2407},"list","bulleted",[2408,2426],{"type":2409,"children":2410},"listItem",[2411],{"type":2215,"children":2412},[2413,2425],{"url":2414,"meta":2415,"type":12,"children":2422},"https:\u002F\u002Fmesimedical.com\u002Finsights\u002Fpulse-wave-velocity-the-hidden-marker-of-arterial-age",[2416,2419],{"id":2417,"value":2418},"rel","noreferrer noopener",{"id":2420,"value":2421},"target","_blank",[2423],{"type":2208,"value":2424},"La vitesse de l’onde de pouls : le marqueur caché de l’âge artériel",{"type":2208,"value":2213},{"type":2409,"children":2427},[2428],{"type":2215,"children":2429},[2430,2438],{"url":2431,"meta":2432,"type":12,"children":2435},"https:\u002F\u002Fmesimedical.com\u002Farterial-assessment",[2433,2434],{"id":2417,"value":2418},{"id":2420,"value":2421},[2436],{"type":2208,"value":2437},"Évaluation artérielle intégrée",{"type":2208,"value":2213},{"type":2215,"children":2440},[2441],{"type":2208,"value":48},{"type":2215,"children":2443},[2444],{"type":2208,"value":48},{"type":2215,"children":2446},[2447,2450],{"type":2208,"marks":2448,"value":2449},[2210],"À propos de la professeure Rosa Maria Bruno",{"type":2208,"value":2213},{"type":2215,"children":2452},[2453],{"type":2208,"value":2454},"La professeure Rosa Maria Bruno est professeure à l’Université Paris Cité et responsable de l’unité de pharmacologie clinique de l’Hôpital Européen Georges Pompidou à Paris. Ses travaux portent sur l’hypertension, le vieillissement vasculaire et l’application clinique de l’évaluation vasculaire non invasive.",{"type":2215,"children":2456},[2457],{"type":2208,"value":48},{"item":2193,"type":2239},{"type":2215,"children":2460},[2461],{"type":2208,"value":48},{"alt":2162,"url":2463,"width":2464,"height":2465,"responsiveImage":2466},"https:\u002F\u002Fwww.datocms-assets.com\u002F160495\u002F1788505431-mesi_testimonial_rosa-maria-bruno_blog-banner.png",1601,901,{"srcSet":2467,"webpSrcSet":2468,"sizes":2469,"src":2470,"width":2471,"height":952,"aspectRatio":2472,"alt":2162,"title":18,"bgColor":2473,"base64":2474},"https:\u002F\u002Fwww.datocms-assets.com\u002F160495\u002F1788505431-mesi_testimonial_rosa-maria-bruno_blog-banner.png?ar64=MjE6OQ&auto=compress&crop=focalpoint&dpr=0.25&fit=crop&w=1440 360w,https:\u002F\u002Fwww.datocms-assets.com\u002F160495\u002F1788505431-mesi_testimonial_rosa-maria-bruno_blog-banner.png?ar64=MjE6OQ&auto=compress&crop=focalpoint&dpr=0.5&fit=crop&w=1440 720w,https:\u002F\u002Fwww.datocms-assets.com\u002F160495\u002F1788505431-mesi_testimonial_rosa-maria-bruno_blog-banner.png?ar64=MjE6OQ&auto=compress&crop=focalpoint&dpr=0.75&fit=crop&w=1440 1080w,https:\u002F\u002Fwww.datocms-assets.com\u002F160495\u002F1788505431-mesi_testimonial_rosa-maria-bruno_blog-banner.png?ar64=MjE6OQ&auto=compress&crop=focalpoint&fit=crop&w=1440 1440w","https:\u002F\u002Fwww.datocms-assets.com\u002F160495\u002F1788505431-mesi_testimonial_rosa-maria-bruno_blog-banner.png?ar64=MjE6OQ&auto=compress&crop=focalpoint&dpr=0.25&fit=crop&fm=webp&w=1440 360w,https:\u002F\u002Fwww.datocms-assets.com\u002F160495\u002F1788505431-mesi_testimonial_rosa-maria-bruno_blog-banner.png?ar64=MjE6OQ&auto=compress&crop=focalpoint&dpr=0.5&fit=crop&fm=webp&w=1440 720w,https:\u002F\u002Fwww.datocms-assets.com\u002F160495\u002F1788505431-mesi_testimonial_rosa-maria-bruno_blog-banner.png?ar64=MjE6OQ&auto=compress&crop=focalpoint&dpr=0.75&fit=crop&fm=webp&w=1440 1080w,https:\u002F\u002Fwww.datocms-assets.com\u002F160495\u002F1788505431-mesi_testimonial_rosa-maria-bruno_blog-banner.png?ar64=MjE6OQ&auto=compress&crop=focalpoint&fit=crop&fm=webp&w=1440 1440w","(max-width: 1440px) 100vw, 1440px","https:\u002F\u002Fwww.datocms-assets.com\u002F160495\u002F1788505431-mesi_testimonial_rosa-maria-bruno_blog-banner.png?ar64=MjE6OQ&auto=compress&crop=focalpoint&fit=crop&w=1440",1440,2.3338735818476497,"#fad75b","data:image\u002Fjpeg;base64,\u002F9j\u002F4AAQSkZJRgABAQAAAQABAAD\u002F2wCEAAoHBwgHBgoICAgLCgoLDhcNDRIWDh0NEQ0VIx0dGBYVFhUaHysjGikoHSEWJDUlKC0vMjIyGSI4PTcwPCsxMi8BCgsLDg0NEA0NFC8dFhwvLy8vLy8vLy8vLy8vLy8vLy8vLy8vLy8vLy8vLy8vLy8vLy8vLy8vLy8vLy8vLy8vL\u002F\u002FAABEIAAsAGAMBIgACEQEDEQH\u002FxAAYAAACAwAAAAAAAAAAAAAAAAAFBgADB\u002F\u002FEAB4QAAEDBAMAAAAAAAAAAAAAAAEAAgMEBhESEzFB\u002F8QAFQEBAQAAAAAAAAAAAAAAAAAAAgH\u002FxAAUEQEAAAAAAAAAAAAAAAAAAAAA\u002F9oADAMBAAIRAxEAPwDWTUBzwg1yV8LINSQr9jntJd4yyAjDiiRrtqsi48j1RArQc404yVFUf\u002F\u002FZ",{"left":2044,"top":2044,"width":2045,"height":2045,"rotate":2044,"vFlip":68,"hFlip":68,"body":2476},"\u003Cg fill=\"none\">\u003Cg id=\"play\">\n\u003Cpath id=\"Vector\" d=\"M17.5956 11.4481L9.71626 6.62959C9.61671 6.56783 9.50235 6.53407 9.38522 6.53185C9.26809 6.52964 9.15253 6.55906 9.05071 6.61701C8.94964 6.67256 8.86544 6.75437 8.80701 6.8538C8.74859 6.95324 8.71809 7.0666 8.71876 7.18193V16.819C8.71809 16.9343 8.74859 17.0477 8.80701 17.1471C8.86544 17.2465 8.94964 17.3283 9.05071 17.3839C9.15253 17.4418 9.26809 17.4713 9.38522 17.469C9.50235 17.4668 9.61671 17.4331 9.71626 17.3713L17.5956 12.5528C17.6905 12.4951 17.7689 12.414 17.8233 12.3173C17.8777 12.2206 17.9062 12.1114 17.9062 12.0004C17.9062 11.8895 17.8777 11.7803 17.8233 11.6836C17.7689 11.5869 17.6905 11.5058 17.5956 11.4481Z\" fill=\"currentColor\"\u002F>\n\u003C\u002Fg>\u003C\u002Fg>",{"left":2044,"top":2044,"width":2045,"height":2045,"rotate":2044,"vFlip":68,"hFlip":68,"body":2478},"\u003Cg fill=\"none\">\u003Cg id=\"arrow-down\">\n\u003Cpath id=\"Vector\" d=\"M19.281 14.0306L12.531 20.7806C12.4614 20.8504 12.3787 20.9057 12.2876 20.9434C12.1966 20.9812 12.099 21.0006 12.0004 21.0006C11.9019 21.0006 11.8043 20.9812 11.7132 20.9434C11.6222 20.9057 11.5394 20.8504 11.4698 20.7806L4.71979 14.0306C4.57906 13.8899 4.5 13.699 4.5 13.5C4.5 13.301 4.57906 13.1101 4.71979 12.9694C4.86052 12.8286 5.05139 12.7496 5.25042 12.7496C5.44944 12.7496 5.64031 12.8286 5.78104 12.9694L11.2504 18.4397V3.75C11.2504 3.55109 11.3294 3.36032 11.4701 3.21967C11.6107 3.07902 11.8015 3 12.0004 3C12.1993 3 12.3901 3.07902 12.5307 3.21967C12.6714 3.36032 12.7504 3.55109 12.7504 3.75V18.4397L18.2198 12.9694C18.3605 12.8286 18.5514 12.7496 18.7504 12.7496C18.9494 12.7496 19.1403 12.8286 19.281 12.9694C19.4218 13.1101 19.5008 13.301 19.5008 13.5C19.5008 13.699 19.4218 13.8899 19.281 14.0306Z\" fill=\"currentColor\"\u002F>\n\u003C\u002Fg>\u003C\u002Fg>",1792751040529]